陈建 助理研究员
硕士生导师
联系邮箱：chenjian034@yeah.net
个人简介
陈建，男，助理研究员，硕士生导师。南开大学生物化学与分子生物学专业获博士学位。
研究领域
1.生物材料在神经系统疾病的应用
主持/参与的项目
1.国家自然科学基金委员会, 青年科学基金项目, 82201636, 净铜纤维素调控肝豆状核变性铜代谢的作用及机制研究, 30万元，2023.1-2025.12，主持
2.福建省科技创新联合基金,引领项目, 2020Y9051,纳米复合型吸附剂用于阿尔兹海默病的治疗, 15万元，2021.8-2024.7，主持
科研成果
1. Lichun Wang#, Jian Chen#, Yamin Chai, Wenyan Han, Jie Shen, Nan Li, Jinyan Lu, Yunzheng Du, Zhuang Liu, Yameng Yu, Jingzhe Dong, Lailiang Ou*. Targeting regulation of the tumour microenvironment induces apoptosis of breast cancer cells by an affinity hemoperfusion adsorbent. Artif Cells Nanomed. Biotechnol 2021, 49(1):325-334. doi: 10.1080/21691401.2021.1902337. (Co-first)
2. Jian Chen, Lichun Wang, Tingting Wang, Chunran Li, Wenyan Han, Yamin Chai, Zhuang Liu,Lailiang Ou*, and Wenzhong Li*. Functionalized Carbon Nanotube-Embedded Poly(vinyl alcohol) Microspheres for Efficient Removal of Tumor Necrosis Factor‑α. ACS Biomater. Sci. Eng. 2020, 6: 4722−4730. doi: 10.1021/acsbiomaterials.9b01916
3. Jian Chen, Yingda Ma, Lichun Wang, Wenyan Han, Yamin Chai, Tingting Wang, Jian Li, Lailiang Ou*. Preparation of chitosan/SiO2-loaded graphene composite beads for efficient removal of bilirubin. Carbon 2019, 143:352-361. doi: 10.1016/j.carbon.2018.11.045.
4. Yingda Ma#, Jian Chen#, Jian Li, Wenyan Han, Yamin Chai, Tingting Wang, Qian Zhang, Lichun Wang, Weichao Wang, Zhexiang Wang and Lailiang Ou*. Selective adsorption of bilirubin against albumin to alkylamine functionalized PVA microspheres. J Biomat Sci-Polyme 2019, 30(5): 337-354. doi: 10.1080/09205063.2018.1553104. (Co-first)
5. Jian Chen, Guanghui Cheng, Yamin Chai, Wenyan Han, Wenhui Zong, Jie Chen, Chunran Li, Weichao Wang, Lailiang Ou*, Yaoting Yu. Preparation of nano-CaCO3/polystyrene nanocomposite beads for efficient bilirubin removal. Colloids and Surfaces B: Biointerfaces 2018, 161:480-487. doi: 10.1016/j.colsurfb.2017.11.017.
6. Jian Chen, Wenyan Han, Jie Chen, Wenhui Zong, Weichao Wang, Yue Wang, Guanghui Cheng, Chunran Li, Lailiang Ou* and Yaoting Yu. High performance of a unique mesoporous polystyrene-based adsorbent for blood purification. Regenerative Biomaterials, 2017, 4(1):31–37. doi: 10.1093/rb/rbw038.
7. Jian Chen, Wenyan Han, Rui Su, Jie Chen, Wenhui Zong, Yue Wang, Weichao Wang, Guanghui Cheng, Lailiang Ou and Yaoting Yu. Non-ionic macroporous polystyrene adsorbents for removal of serum toxins in liver failure by hemoperfusion. Artif Cells Nanomed. Biotechnol 2017, 45(1): 174-183. doi: 10.3109/21691401.2016.1138494.
8.专利：一种净铜纤维素及其制备方法和在制备口服治疗肝豆状核变性药物中的应用、陈建、陈万金、王柠、付莹、2025.3、2025102846785
（更新于2025年9月）
